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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC3
All Species:
14.24
Human Site:
S121
Identified Species:
39.17
UniProt:
Q6UUV7
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UUV7
NP_001036039.1
619
66959
S121
P
G
R
Q
F
D
G
S
A
F
G
A
N
Y
S
Chimpanzee
Pan troglodytes
XP_510592
618
66846
S121
P
G
R
Q
F
D
G
S
A
F
G
A
N
Y
S
Rhesus Macaque
Macaca mulatta
XP_001097976
618
66835
S121
P
G
R
Q
F
D
G
S
A
F
G
P
N
Y
S
Dog
Lupus familis
XP_545865
640
69541
S143
P
A
R
Q
F
D
G
S
T
F
G
A
S
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91X84
619
67008
N121
P
G
R
Q
F
D
G
N
A
F
A
A
S
Y
S
Rat
Rattus norvegicus
Q3LRZ1
691
73127
S128
Y
P
R
H
I
D
S
S
P
Y
S
P
A
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
K123
R
R
P
L
S
V
D
K
H
G
R
Q
V
D
S
Frog
Xenopus laevis
Q52KS4
632
69330
Q121
P
V
E
K
H
G
R
Q
C
D
S
S
P
Y
G
Zebra Danio
Brachydanio rerio
XP_698544
527
57276
L57
V
Y
A
E
N
E
D
L
C
L
F
F
N
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
82.3
N.A.
88.8
40.8
N.A.
N.A.
38.5
49.3
39.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99
87.5
N.A.
93.6
54.2
N.A.
N.A.
53.5
62.8
52.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
26.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
33.3
N.A.
N.A.
6.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
0
0
45
0
12
45
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
23
0
0
12
0
0
0
12
0
% D
% Glu:
0
0
12
12
0
12
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
56
0
0
0
0
56
12
12
0
0
0
% F
% Gly:
0
45
0
0
0
12
56
0
0
12
45
0
0
0
12
% G
% His:
0
0
0
12
12
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
0
12
0
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
0
0
0
45
0
0
% N
% Pro:
67
12
12
0
0
0
0
0
12
0
0
23
12
0
12
% P
% Gln:
0
0
0
56
0
0
0
12
0
0
0
12
0
0
0
% Q
% Arg:
12
12
67
0
0
0
12
0
0
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
12
0
12
56
0
0
23
12
23
0
67
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% T
% Val:
12
12
0
0
0
12
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
0
0
0
0
12
0
0
0
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _